講師資料
Talks：
Precision Digital Dentistry and Sleep Medicine: Interdisciplinary Innovation in Mandibular Advancement Device Therapy for Sleep Disordered Breathing.
精準數位牙科與睡眠醫學：下顎前移裝置治療睡眠呼吸障礙之跨學科整合
Name：
羅士傑（Shih-Chieh Lo）
Position：
1. PhD Candidate
2. Chief Executive Officer and Dental Director, Leading Dental Group
Affiliation：
1. Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan
2. Department of Administer/Dentistry, Leading Dental Group, Taipei, Taiwan
Email：
Photo：
Research Interests：
Clear aligners orthodontic treatment, Dental sleep medicine
Selected Publications：
1. Lo SC, Hsu YS, Lin YH, Kuo YE, Chen TY, Yang CC. Mandibular Advancement for Obstructive Sleep Apnea: Efficacy and the Trade-off of Expiratory Velopharyngeal Obstruction During Sleep Endoscopy – An Exploratory Observational Study. Nat Sci Sleep. 2026;18:598380, https://doi.org/10.2147/NSS.S598380
2. Hsu YS, Ke YK, Kuo TBJ, Chang Y, Jacobowitz O, Lin CM, Lo SC, Yang CCH. Expiratory Velopharyngeal Obstruction: Sleep Endoscopy-Guided Treatment Strategies to Prevent Oral Breathing During Sleep. Otolaryngol Head Neck Surg. 2024 Nov;171(5):1591-1600. doi: 10.1002/ohn.902.
Abstract：
Sleep-disordered breathing, particularly obstructive sleep apnea, requires treatment strategies that are effective, patient-centered, and adaptable to individual craniofacial, dental, and functional characteristics. Mandibular advancement devices (MADs) have become an important non-continuous positive airway pressure treatment option; however, clinical outcomes remain influenced by patient selection, device design, mandibular titration, occlusal status, temporomandibular joint function, and long-term adherence.
This presentation explores how precision digital dentistry can advance MAD therapy through interdisciplinary collaboration between sleep medicine, dentistry, orthodontics, biomedical engineering, and digital health. Digital intraoral scanning, three-dimensional craniofacial assessment, virtual treatment planning, computer-aided design and manufacturing, and objective sleep and physiological monitoring together offer a pathway from conventional appliance fabrication toward individualized, data-informed therapy.
The presentation will propose an integrated clinical framework encompassing sleep-disordered breathing screening, phenotypic and dental evaluation, digital design and fabrication of MADs, titration strategies, follow-up assessment, and monitoring of therapeutic efficacy and dentofacial adverse effects. Particular attention will be given to the potential role of digital workflows in improving reproducibility, comfort, adherence, interdisciplinary communication, and longitudinal outcome evaluation.
By positioning MAD therapy at the intersection of precision dentistry and sleep medicine, this work aims to establish a translational direction for more personalized, measurable, and sustainable management of sleep-disordered breathing. It further highlights future priorities in optimizing digital MAD design, refining patient stratification, and evaluating treatment outcomes.
睡眠呼吸障礙，尤其是阻塞型睡眠呼吸中止症，需要兼具療效、以病人為中心，並能因應個別顱顏、牙科與功能特徵的治療策略。下顎前移裝置（mandibular advancement device, MAD）已成為非持續性正壓呼吸器治療的重要選項；然而，其臨床療效仍受病人篩選、裝置設計、下顎前移調整、咬合狀態、顳顎關節功能及長期配戴依從性等因素影響。
本演講探討精準數位牙科如何透過睡眠醫學、牙科、齒顎矯正、生物醫學工程及數位健康之跨學科協作，推動 MAD 治療的創新發展。數位口內掃描、三維顱顏評估、虛擬治療規劃、電腦輔助設計與製造，以及客觀睡眠與生理監測等技術，可使治療流程由傳統裝置製作進一步邁向個人化、數據導向的治療模式。
本演講將提出一項整合式臨床架構，涵蓋睡眠呼吸障礙之篩檢、表型與牙科評估、MAD 的數位設計與製作、下顎前移調整策略、追蹤評估，以及治療療效與牙齒顎面副作用之監測。並特別討論數位工作流程在提升治療可再現性、配戴舒適度、病人依從性、跨專業溝通及長期療效評估上的潛在價值。
透過將 MAD 治療定位於精準牙科與睡眠醫學的交會點，本研究旨在建立睡眠呼吸障礙更個人化、可量測且具長期可持續性的治療與轉譯研究方向，並進一步提出未來在數位 MAD 設計優化、病人分層及治療成效評估上的重要課題。
2026年會：